Faculty

Erwin Bottinger

Bio

After years of dedicated service, Professor Erwin Böttinger, MD, will step down as the Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai (HPI.MS) on March 31, 2023. Starting April 3rd, Professor Böttinger will assume his new responsibilities as Chief Executive Officer of the Wyss Center for Bio and Neuroengineering in Geneva, Switzerland. We thank Professor Böttinger for his vision that led to the founding of HPI.MS in 2019, and his commitment and enthusiasm, which helped shape the institute into the robust research hub it is today.  

Professor Böttinger pioneered groundbreaking implementations of personalized medicine and digital health. He joined the Icahn School of Medicine at Mount Sinai in 2004, served as Chief Executive Officer of the Berlin Institute of Health from 2015-2017, served as the Head of the Digital Health Center at the Hasso Plattner Institute in Potsdam since 2017, and became a founding Co-Director of HPI.MS in 2019. During his tenure at HPI.MS, he led the Digital Discovery Program, which focuses on patient-centric health studies using wearable and mobile technology, as well as leading several collaborations and mentoring the next generation of researchers. Professor Böttinger will remain a tenured professor at the Windreich Department of AI and Human Health at the Icahn School of Medicine at Mount Sinai. We wish him all the best in his new role. 

Bio

After years of dedicated service, Professor Erwin Böttinger, MD, will step down as the Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai (HPI.MS) on March 31, 2023. Starting April 3rd, Professor Böttinger will assume his new responsibilities as Chief Executive Officer of the Wyss Center for Bio and Neuroengineering in Geneva, Switzerland. We thank Professor Böttinger for his vision that led to the founding of HPI.MS in 2019, and his commitment and enthusiasm, which helped shape the institute into the robust research hub it is today.  

Professor Böttinger pioneered groundbreaking implementations of personalized medicine and digital health. He joined the Icahn School of Medicine at Mount Sinai in 2004, served as Chief Executive Officer of the Berlin Institute of Health from 2015-2017, served as the Head of the Digital Health Center at the Hasso Plattner Institute in Potsdam since 2017, and became a founding Co-Director of HPI.MS in 2019. During his tenure at HPI.MS, he led the Digital Discovery Program, which focuses on patient-centric health studies using wearable and mobile technology, as well as leading several collaborations and mentoring the next generation of researchers. Professor Böttinger will remain a tenured professor at the Windreich Department of AI and Human Health at the Icahn School of Medicine at Mount Sinai. We wish him all the best in his new role. 

Publications

March, 2021

Outcomes of Patients on Maintenance Dialysis Hospitalized with COVID-19

Journal | CJASN

HPI·MS Authors

Zahi Fayad

Erwin Bottinger

Alex Charney

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Lili Chan, Suraj K Jaladanki, Sulaiman Somani, Ishan Paranjpe, Arvind Kumar, Shan Zhao, Lewis Kaufman, Staci Leisman, Shuchita Sharma, John Cijiang He, Barbara Murphy, Zahi A Fayad, Matthew A Levin, Erwin P Bottinger, Alexander W Charney, Benjamin S Glicksberg, Steven G Coca, Girish N Nadkarni

Journal

CJASN

Open Publication

February, 2021

Association of SARS-CoV-2 viral load at admission with in-hospital acute kidney injury: A retrospective cohort study

Journal | PLOS ONE

HPI·MS Authors

Erwin Bottinger

Zahi Fayad

Alex Charney

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Ishan Paranjpe, Kumardeep Chaudhary, Kipp W. Johnson, Suraj K. Jaladanki, Shan Zhao, Jessica K. De Freitas, Elisabet Pujdas, Fayzan Chaudhry, Erwin P. Bottinger, Matthew A. Levin, Zahi A. Fayad, Alexander W. Charney, Jane Houldsworth, Carlos Cordon-Cardo, Benjamin S. Glicksberg, Girish N. Nadkarni

Journal

PLOS ONE

Open Publication

February, 2021

Use of Physiological Data From a Wearable Device to Identify SARS-CoV-2 Infection and Symptoms and Predict COVID-19 Diagnosis: Observational Study

Journal | Journal of Medical Internet Research

HPI·MS Authors

Robert Hirten

Matteo Danieletto

Micol Zweig

Sparshdeep (Shelly) Kaur

Alex Charney

Erwin Bottinger

Girish Nadkarni

Zahi Fayad

8 HPI•MS authors

Full list of authors

Robert P Hirten; Matteo Danieletto; Lewis Tomalin; Katie Hyewon Choi; Micol Zweig; Eddye Golden; Sparshdeep Kaur; Drew Helmus; Anthony Biello; Renata Pyzik; Alexander Charney; Riccardo Miotto; Benjamin S Glicksberg; Matthew Levin; Ismail Nabeel; Judith Aberg; David Reich; Dennis Charney; Erwin P Bottinger; Laurie Keefer; Mayte Suarez-Farinas; Girish N Nadkarni; Zahi A Fayad

Journal

Journal of Medical Internet Research

Open Publication

January, 2021

Federated Learning of Electronic Health Records to Improve Mortality Prediction in Hospitalized Patients With COVID-19: Machine Learning Approach

Journal | JMIR Med Inform

HPI·MS Authors

Alex Charney

Erwin Bottinger

Zahi Fayad

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Akhil Vaid, Suraj K Jaladanki, Jie Xu, Shelly Teng, Arvind Kumar, Samuel Lee, Sulaiman Somani, Ishan Paranjpe, Jessica K De Freitas, Tingyi Wanyan, Kipp W Johnson, Mesude Bicak, Eyal Klang, Young Joon Kwon, Anthony Costa, Shan Zhao, Riccardo Miotto, Alexander W Charney, Erwin Böttinger, Zahi A Fayad, Girish N Nadkarni, Fei Wang, Benjamin S Glicksberg

Journal

JMIR Med Inform

Open Publication

January, 2021

Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity

Journal | Science Translational Medicine

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Hongliu Yang, Xiangchen Gu, Xin Sheng, Yi-An Ko, Rachel Kember, Renae L. Judy, Scott M. Damrauer, Daniel J. Rader, Girish N Nadkarni, Ruth JF Loos, Vy Thi Ha My, Kumardeep Chaudhary, Erwin P Bottinger, Chengxiang Qiu, Jihwan Park, Shizheng Huang, Christopher Brown, Shreeram Akilesh, Matthew Palmer, Regeneron Genetics Center, Katalin Susztak

Journal

Science Translational Medicine

Open Publication

January, 2021

AKI in Hospitalized Patients with COVID-19

Journal | Journal of the American Society of Nephrology

HPI·MS Authors

Zahi Fayad

Alex Charney

Erwin Bottinger

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Lili Chan, Kumardeep Chaudhary, Aparna Saha, Kinsuk Chauhan, Akhil Vaid, Shan Zhao, Ishan Paranjpe, Sulaiman Somani, Felix Richter, Riccardo Miotto, Anuradha Lala, Arash Kia, Prem Timsina, Li Li, Robert Freeman, Rong Chen, Jagat Narula, Allan C. Just, Carol Horowitz, Zahi Fayad, Carlos Cordon-Cardo, Eric Schadt, Matthew A. Levin, David L. Reich, Valentin Fuster, Barbara Murphy, John C. He, Alexander W. Charney, Erwin P. Böttinger, Benjamin S. Glicksberg, Steven G. Coca, Girish N. Nadkarni and on behalf of the Mount Sinai COVID Informatics Center (MSCIC)

Journal

Journal of the American Society of Nephrology

Open Publication

November, 2020

Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City

Journal | BMJ Open

HPI·MS Authors

Matteo Danieletto

Manbir Singh

Zahi Fayad

Erwin Bottinger

Alex Charney

Girish Nadkarni

6 HPI•MS authors

Full list of authors

Ishan Paranjpe, Adam J Russak, Jessica K De Freitas, Anuradha Lala, Riccardo Miotto, Akhil Vaid, Kipp W Johnson, Matteo Danieletto, Eddye Golden, Dara Meyer, Manbir Singh, Sulaiman Somani, Arjun Kapoor, Ross O'Hagan, Sayan Manna, Udit Nangia, Suraj K Jaladanki, Paul O’Reilly, Laura M Huckins, Patricia Glowe, Arash Kia, Prem Timsina, Robert M Freeman, Matthew A Levin, Jeffrey Jhang, Adolfo Firpo, Patricia Kovatch, Joseph Finkelstein, Judith A Aberg, Emilia Bagiella, Carol R Horowitz, Barbara Murphy, Zahi A Fayad, Jagat Narula, Eric J Nestler, V Fuster, Carlos Cordon-Cardo, Dennis Charney, David L Reich, Allan Just, Erwin P Bottinger, Alexander W Charney, Benjamin S Glicksberg, Girish N Nadkarni

Journal

BMJ Open

Open Publication

November, 2020

Phe2vec: Automated Disease Phenotyping based on Unsupervised Embeddings from Electronic Health Records

Journal | medRxiv

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Jessica K De Freitas, Kipp W Johnson, Eddye Golden, Girish N Nadkarni, Joel T Dudley, Erwin P Bottinger, Benjamin S Glicksberg, Riccardo Miotto

Journal

medRxiv

Open Publication

November, 2020

Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation

Journal | JMIR Medical Informatics

HPI·MS Authors

Matteo Danieletto

Manbir Singh

Erwin Bottinger

Zahi Fayad

Alex Charney

Girish Nadkarni

6 HPI•MS authors

Full list of authors

Akhil Vaid, Sulaiman Somani, Adam J Russak, Jessica K De Freitas, Fayzan F Chaudhry, Ishan Paranjpe, Kipp W Johnson, Samuel J Lee, Riccardo Miotto, Shan Zhao, Noam Beckmann, Nidhi Naik, Kodi Arfer, Arash Kia, Prem Timsina, Anuradha Lala, Manish Paranjpe, Patricia Glowe, Eddye Golden, Matteo Danieletto, Manbir Singh, Dara Meyer, Paul F O'Reilly, Laura H Huckins, Patricia Kovatch, Joseph Finkelstein, Robert M Freeman, Edgar Argulian, Andrew Kasarskis, Bethany Percha, Judith A Aberg, Emilia Bagiella, Carol R Horowitz, Barbara Murphy, Eric J Nestler, Eric E Schadt, Judy H Cho, Carlos Cordon-Cardo, Valentin Fuster, Dennis S Charney, David L Reich, Erwin P Bottinger, Matthew A Levin, Jagat Narula, Zahi A Fayad, Allan Just, Alexander W Charney, Girish N Nadkarni, Benjamin S Glicksberg

Journal

JMIR Medical Informatics

Open Publication

November, 2020

Utilization of deep learning for subphenotype identification in sepsis-associated acute kidney injury

Journal | Acute Kidney Injury and ICU Nephrology

HPI·MS Authors

Erwin Bottinger

Girish Nadkarni

2 HPI•MS authors

Full list of authors

Kumardeep Chaudhary, Akhil Vaid, Áine Duffy, Ishan Paranjpe, Suraj Jaladanki, Manish Paranjpe, Kipp Johnson, Avantee Gokhale, Pattharawin Pattharanitima, Kinsuk Chauhan, Ross O’Hagan, Tielman Van Vleck, Steven G Coca, Richard Cooper, Benjamin Glicksberg, Erwin P Bottinger, Lili Chan, Girish N Nadkarni

Journal

Acute Kidney Injury and ICU Nephrology

Open Publication

October, 2020

A Machine Learning Approach for Non-Invasive Diagnosis of Metabolic Syndrome

Journal | 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE)

HPI·MS Authors

Jan Philipp Sachs

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Suparno Datta, Anne Schraplau, Harry Freitas Da Cruz, Jan Philipp Sachs, Frank Mayer, Erwin Böttinger

Conference

2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE)

Open Publication

October, 2020

Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury

Journal | Clinical Journal of the American Society of Nephrology

HPI·MS Authors

Erwin Bottinger

Girish Nadkarni

2 HPI•MS authors

Full list of authors

Kumardeep Chaudhary, Akhil Vaid, Áine Duffy, Ishan Paranjpe, Suraj Jaladanki, Manish Paranjpe, Kipp Johnson, Avantee Gokhale, Pattharawin Pattharanitima, Kinsuk Chauhan, Ross O’Hagan, Tielman Van Vleck, Steven G. Coca, Richard Cooper, Benjamin Glicksberg, Erwin P. Bottinger, Lili Chan and Girish N. Nadkarni

Clinical Journal of the American Society of Nephrology

Open Publication

September, 2020

Event Log Generation in a Health System: A Case Study

Journal | 18th International Conference on Business Process Management

HPI·MS Authors

Jan Philipp Sachs

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Simon Remy, Luis Pufahl, Jan Philipp Sachs, Erwin Bottinger, Mathias Weske

Conference

18th International Conference on Business Process Management

Open Publication

September, 2020

Trans-ethnic and ancenstry-specific blood-cell genetics in 746,667 individuals from 5 global populations

Journal | Cell

HPI·MS Authors

Erwin Bottinger

Girish Nadkarni

2 HPI•MS authors

Full list of authors

Ming-Huei Chen, Laura M Raffield, Abdou Mousas, Saori Sakaue, Jennifer E Huffman, Tao Jiang, Parsa Akbari, Dragana Vuckovic, Erik L Bao, Arden Moscati, Xue Zhong, Regina Manansala, Véronique Laplante, Minhui Chen, Ken Sin Lo, Huijun Qian, Caleb A Lareau, Mélissa Beaudoin, Masato Akiyama, Traci M Bartz, Yoav Ben-Shlomo, Andrew Beswick, Jette Bork-Jensen, Erwin P Bottinger, Jennifer A Brody, Frank JA van Rooij, Kumaraswamynaidu Chitrala, Kelly Cho, Hélène Choquet, Adolfo Correa, John Danesh, Emanuele Di Angelantonio, Niki Dimou, Jingzhong Ding, Paul Elliott, Tõnu Esko, Michele K Evans, James S Floyd, Linda Broer, Niels Grarup, Michael H Guo, Andreas Greinacher, Jeff Haessler, Torben Hansen, Joanna MM Howson, Wei Huang, Eric Jorgenson, Tim Kacprowski, Mika Kähönen, Yoichiro Kamatani, Masahiro Kanai, Savita Karthikeyan, Fotis Koskeridis, Leslie A Lange, Terho Lehtimäki, Markus M Lerch, Allan Linneberg, Yongmei Liu, Leo-Pekka Lyytikäinen, Ani Manichaikul, Koichi Matsuda, Karen L Mohlke, Nina Mononen, Yoshinori Murakami, Girish N Nadkarni, Matthias Nauck, Kjell Nikus, Willem H Ouwehand, Nathan Pankratz, Oluf Pedersen, Michael Preuss, Bruce M Psaty, Olli T Raitakari, David J Roberts, Stephen S Rich, Benjamin AT Rodriguez, Jonathan D Rosen, Jerome I Rotter, Petra Schubert, Cassandra N Spracklen, Praveen Surendran, Hua Tang, Jean-Claude Tardif, Mohsen Ghanbari, Uwe Völker, Henry Völzke, Nicholas A Watkins, Alan B Zonderman, Peter WF Wilson, Yun Li, Adam S Butterworth, Jean-François Gauchat, Charleston WK Chiang, Bingshan Li, Ruth JF Loos, William J Astle, Evangelos Evangelou, Vijay G Sankaran, Yukinori Okada, Nicole Soranzo, Andrew D Johnson, Alexander P Reiner, Paul L Auer, Guillaume Lettre

Journal

Cell

Open Publication

September, 2020

The polygenic and monogenic basis of blood traits and diseases

Journal | Cell

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Dragana Vuckovic, Erik L Bao, Parsa Akbari, Caleb A Lareau, Abdou Mousas, Tao Jiang, Ming-Huei Chen, Laura M Raffield, Manuel Tardaguila, Jennifer E Huffman, Scott C Ritchie, Karyn Megy, Hannes Ponstingl, Christopher J Penkett, Patrick K Albers, Emilie M Wigdor, Saori Sakaue, Arden Moscati, Regina Manansala, Ken Sin Lo, Huijun Qian, Masato Akiyama, Traci M Bartz, Yoav Ben-Shlomo, Andrew Beswick, Jette Bork-Jensen, Erwin P Bottinger, Jennifer A Brody, Frank JA van Rooij, Kumaraswamy N Chitrala, Kelly Cho, Hélène Choquet, John Danesh, Emanuele Di Angelantonio, Niki Dimou, Jingzhong Ding, Paul Elliott, Tõnu Esko, Michele K Evans, Stephan B Felix, James S Floyd, Linda Broer, Niels Grarup, Michael Guo, Andreas Greinacher, Jeff Haessler, Torben Hansen, Joanna Howson, Wei Huang, Eric Jorgenson, Tim Kacprowski, Mika Kähönen, Yoichiro Kamatani, Masahiro Kanai, Savita Karthikeyan, Fotis Koskeridis, Leslie A Lange, Terho Lehtimäki, Allan Linneberg, Yongmei Liu, Leo-Pekka Lyytikäinen, Ani Manichaikul, Koichi Matsuda, Karen L Mohlke, Nina Mononen, Yoshinori Murakami, Girish Nadkarni, Kjell Nikus, Nathan Pankratz, Oluf Pedersen, Michael Preuss, Bruce M Psaty, Olli T Raitakari, Stephen S Rich, Benjamin AT Rodriguez, Jonathan D Rosen, Jerome I Rotter, Petra Schubert, Cassandra N Spracklen, Praveen Surendran, Hua Tang, Jean-Claude Tardif, Mohsen Ghanbari, Uwe Völker, Henry Völzke, Nicholas A Watkins, Stefan Weiss, Na Cai, Kousik Kundu, Stephen Watt, Klaudia Walter, Alan B Zonderman, Peter WF Wilson, Yun Li, Ruth JF Loos, Julian Charles Knight, Michel Georges, Oliver Stegle, Evangelos Evangelou, Yukinori Okada, David J Roberts, Michael Inouye, Andrew D Johnson, Paul L Auer, William J Astle, Alexander P Reiner, Adam S Butterworth, Willem Hendrik Ouwehand, Guillaume Lettre, Vijay G Sankaran, Nicole Soranzo

Journal

Cell

Open Publication

August, 2020

Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization For COVID-19

Journal | Journal of General Internal Medicine

HPI·MS Authors

Erwin Bottinger

Zahi Fayad

Alex Charney

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Sulaiman Somani, Felix Richter, Valentin Fuster, Jessica De Freitas, Nidhi Naik, Keith Sigel, Mount Sinai Covid Informatics Center, Erwin P Boettinger, Matthew A Levin, Zahi Fayad, Allan C Just, Alexander Charney, Shan Zhao, Benjamin S Glicksberg, Anuradha Lala, Girish Nadkarni

Journal

Journal of General Internal Medicine

Open Publication

July, 2020

Wearable Devices Are Well Accepted by Patients in the Study and Management of Inflammatory Bowel Disease: A Survey Study

Journal | Digestive Diseases and Sciences

HPI·MS Authors

Robert Hirten

Matteo Danieletto

Erwin Bottinger

3 HPI•MS authors

Full list of authors

Robert P Hirten, Stephanie Stanley, Matteo Danieletto, Zachary Borman, Ari Grinspan, Prameela Rao, Jenny Sauk, Lin Chang, Bert Arnrich, Erwin Bӧttinger, Laurie Keefer, Bruce E Sands

Journal

Digestive Diseases and Sciences

Open Publication

June, 2020

Coronavirus 2019 and People Living With Human Immunodeficiency Virus: Outcomes for Hospitalized Patients in New York City

Journal | Clinical Infectious Diseases

HPI·MS Authors

Erwin Bottinger

Zahi Fayad

Alex Charney

Girish Nadkarni

4 HPI•MS authors

Full list of authors

Keith Sigel, Talia Swartz, Eddye Golden, Ishan Paranjpe, Sulaiman Somani, Felix Richter, Jessica K De Freitas, Riccardo Miotto, Shan Zhao, Paz Polak, Tinaye Mutetwa, Stephanie Factor, Saurabh Mehandru, Michael Mullen, Francesca Cossarini, Erwin Bottinger, Zahi Fayad, Miriam Merad, Sacha Gnjatic, Judith Aberg, Alexander Charney, Girish Nadkarni, Benjamin S Glicksberg

Journal

Clinical Infectious Diseases

Open Publication

June, 2020

Genetic analyses of diverse populations improves discovery for complex traits

Journal | Nature

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Genevieve L Wojcik, Mariaelisa Graff, Katherine K Nishimura, Ran Tao, Jeffrey Haessler, Christopher R Gignoux, Heather M Highland, Yesha M Patel, Elena P Sorokin, Christy L Avery, Gillian M Belbin, Stephanie A Bien, Iona Cheng, Sinead Cullina, Chani J Hodonsky, Yao Hu, Laura M Huckins, Janina Jeff, Anne E Justice, Jonathan M Kocarnik, Unhee Lim, Bridget M Lin, Yingchang Lu, Sarah C Nelson, Sung-Shim L Park, Hannah Poisner, Michael H Preuss, Melissa A Richard, Claudia Schurmann, Veronica W Setiawan, Alexandra Sockell, Karan Vahi, Marie Verbanck, Abhishek Vishnu, Ryan W Walker, Kristin L Young, Niha Zubair, Victor Acuña-Alonso, Jose Luis Ambite, Kathleen C Barnes, Eric Boerwinkle, Erwin P Bottinger, Carlos D Bustamante, Christian Caberto, Samuel Canizales-Quinteros, Matthew P Conomos, Ewa Deelman, Ron Do, Kimberly Doheny, Lindsay Fernández-Rhodes, Myriam Fornage, Benyam Hailu, Gerardo Heiss, Brenna M Henn, Lucia A Hindorff, Rebecca D Jackson, Cecelia A Laurie, Cathy C Laurie, Yuqing Li, Dan-Yu Lin, Andres Moreno-Estrada, Girish Nadkarni, Paul J Norman, Loreall C Pooler, Alexander P Reiner, Jane Romm, Chiara Sabatti, Karla Sandoval, Xin Sheng, Eli A Stahl, Daniel O Stram, Timothy A Thornton, Christina L Wassel, Lynne R Wilkens, Cheryl A Winkler, Sachi Yoneyama, Steven Buyske, Christopher A Haiman, Charles Kooperberg, Loic Le Marchand, Ruth JF Loos, Tara C Matise, Kari E North, Ulrike Peters, Eimear E Kenny, Christopher S Carlson

Journal

Nature

Open Publication

April, 2020

Clinical Characteristics of Hospitalized COVID-19 Patients in New York City

Journal | medRxiv

HPI·MS Authors

Matteo Danieletto

Manbir Singh

Zahi Fayad

Erwin Bottinger

Alex Charney

Girish Nadkarni

6 HPI•MS authors

Full list of authors

Ishan Paranjpe, Adam Russak, Jessica K De Freitas, Anuradha Lala, Riccardo Miotto, Akhil Vaid, Kipp W Johnson, Matteo Danieletto, Eddye Golden, Dara Meyer, Manbir Singh, Sulaiman Somani, Sayan Manna, Udit Nangia, Arjun Kapoor, Ross O'Hagan, Paul F O'Reilly, Laura M Huckins, Patricia Glowe, Arash Kia, Prem Timsina, Robert M Freeman, Matthew A Levin, Jeffrey Jhang, Adolfo Firpo, Patricia Kovatch, Joseph Finkelstein, Judith A Aberg, Emilia Bagiella, Carol R Horowitz, Barbara Murphy, Zahi A Fayad, Jagat Narula, Eric J Nestler, Valentin Fuster, Carlos Cordon-Cardo, Dennis S Charney, David L Reich, Allan C Just, Erwin P Bottinger, Alexander W Charney, Benjamin S Glicksberg, Girish Nadkarni, Mount Sinai Covid Informatics Center

Journal

medRxiv

Open Publication

March, 2020

Association of APOL1 Risk Genotype and Air Pollution for Kidney Disease

Journal | Clinical Journal of the American Society of Nephrology

HPI·MS Authors

Erwin Bottinger

Girish Nadkarni

2 HPI•MS authors

Full list of authors

Ishan Paranjpe, Kumardeep Chaudhary, Manish Paranjpe, Ross O’Hagan, Sayan Manna, Suraj Jaladanki, Arjun Kapoor, Carol Horowitz, Nicholas DeFelice, Richard Cooper, Benjamin Glicksberg, Erwin P Bottinger, Allan C Just, Girish N Nadkarni

Journal

Clinical Journal of the American Society of Nephrology

Open Publication

March, 2020

Association of Apolipoprotein L1 Risk Genotype and Air Pollution for Kidney Disease

Journal | Clinical Journal of American Society of Nephrology

HPI·MS Authors

Erwin Bottinger

Girish Nadkarni

2 HPI•MS authors

Full list of authors

Ishan Paranjpe, Kumardeep Chaudhary, Manish Paranjpe, Ross O’Hagan, Sayan Manna, Suraj Jaladanki, Arjun Kapoor, Carol Horowitz, Nicholas Defelice, Rachel Jia, Benjamin Glicksberg, Richard Cooper, Erwin P Bottinger, Allan C. Just, Girish N. Nadkarni

Journal

Clinical Journal of American Society of Nephrology

Open Publication

October, 2019

Target genes, variants, tissues, and transcriptional pathways influencing human serum urate levels

Journal | Nature Genetics

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Adrienne Tin, Jonathan Marten, Victoria L Halperin Kuhns, Yong Li, Matthias Wuttke, Holger Kirsten, Karsten B Sieber, Chengxiang Qiu, Mathias Gorski, Zhi Yu, Ayush Giri, Gardar Sveinbjornsson, Man Li, Audrey Y Chu, Anselm Hoppmann, Luke J O’Connor, Bram Prins, Teresa Nutile, Damia Noce, Masato Akiyama, Massimiliano Cocca, Sahar Ghasemi, Peter J van Der Most, Katrin Horn, Yizhe Xu, Christian Fuchsberger, Sanaz Sedaghat, Saima Afaq, Najaf Amin, Johan Ärnlöv, Stephan JL Bakker, Nisha Bansal, Daniela Baptista, Sven Bergmann, Mary L Biggs, Ginevra Biino, Eric Boerwinkle, Erwin P Bottinger, Thibaud S Boutin, Marco Brumat, Ralph Burkhardt, Eric Campana, Archie Campbell, Harry Campbell, Robert J Carroll, Eulalia Catamo, John C Chambers, Marina Ciullo, Maria Pina Concas, Josef Coresh, Tanguy Corre, Daniele Cusi, Sala Cinzia Felicita, Martin H de Borst, Alessandro De Grandi, Renée de Mutsert, Aiko PJ de Vries, Graciela Delgado, Ayşe Demirkan, Olivier Devuyst, Katalin Dittrich, Kai-Uwe Eckardt, Georg Ehret, Karlhans Endlich, Michele K Evans, Ron T Gansevoort, Paolo Gasparini, Vilmantas Giedraitis, Christian Gieger, Giorgia Girotto, Martin Gögele, Scott D Gordon, Daniel F Gudbjartsson, Vilmundur Gudnason, Toomas Haller, Pavel Hamet, Tamara B Harris, Caroline Hayward, Andrew A Hicks, Edith Hofer, Hilma Holm, Wei Huang, Nina Hutri-Kähönen, Shih-Jen Hwang, M Arfan Ikram, Raychel M Lewis, Erik Ingelsson, Johanna Jakobsdottir, Ingileif Jonsdottir, Helgi Jonsson, Peter K Joshi, Navya Shilpa Josyula, Bettina Jung, Mika Kähönen, Yoichiro Kamatani, Masahiro Kanai, Shona M Kerr, Wieland Kiess, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Antje Körner, Peter Kovacs, Bernhard K Krämer, Florian Kronenberg, Michiaki Kubo, Brigitte Kühnel, Martina La Bianca, Leslie A Lange, Benjamin Lehne, Terho Lehtimäki, Jun Liu, Markus Loeffler, Ruth JF Loos, Leo-Pekka Lyytikäinen, Reedik Magi, Anubha Mahajan, Nicholas G Martin, Winfried März, Deborah Mascalzoni, Koichi Matsuda, Christa Meisinger, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Christopher J O’Donnell, Otis D Wilson, J Michael Gaziano, Pashupati P Mishra, Karen L Mohlke, Nina Mononen, Grant W Montgomery, Dennis O Mook-Kanamori, Martina Müller-Nurasyid, Girish N Nadkarni, Mike A Nalls, Matthias Nauck, Kjell Nikus, Boting Ning, Ilja M Nolte, Raymond Noordam, Jeffrey R O’Connell, Isleifur Olafsson, Sandosh Padmanabhan, Brenda WJH Penninx, Thomas Perls, Annette Peters, Mario Pirastu, Nicola Pirastu, Giorgio Pistis

Journal

Nature Genetics

Open Publication

September, 2019

Towards a fine-scale population health monitoring system

Journal | bioRxiv

HPI·MS Authors

Erwin Bottinger

1 HPI•MS authors

Full list of authors

Gillian M Belbin, Stephane Wenric, Sinead Cullina, Benjamin S Glicksberg, Arden Moscati, Genevieve L Wojcik, Ruhollah Shemirani, Noam D Beckmann, Ariella Cohain, Elena P Sorokin, Danny S Park, Jose-Luis Ambite, Steve Ellis, Adam Auton, CBIPM Genomics Team, CBIPM Genomics Team, Regeneron Genetics Center, Erwin P. Bottinger, Judy H Cho, Ruth JF Loos, Noura S Abul-husn, Noah A Zaitlen, Christopher R Gignoux, Eimear E Kenny

Journal

bioRxiv

Open Publication

June, 2019

Genetic analyses of diverse populations improves discovery for complex traits

Journal | Nature

HPI·MS Authors

Girish Nadkarni

Erwin Bottinger

2 HPI•MS authors

Full list of authors

Genevieve L Wojcik, Mariaelisa Graff, Katherine K Nishimura, Ran Tao, Jeffrey Haessler, Christopher R Gignoux, Heather M Highland, Yesha M Patel, Elena P Sorokin, Christy L Avery, Gillian M Belbin, Stephanie A Bien, Iona Cheng, Sinead Cullina, Chani J Hodonsky, Yao Hu, Laura M Huckins, Janina Jeff, Anne E Justice, Jonathan M Kocarnik, Unhee Lim, Bridget M Lin, Yingchang Lu, Sarah C Nelson, Sung-Shim L Park, Hannah Poisner, Michael H Preuss, Melissa A Richard, Claudia Schurmann, Veronica W Setiawan, Alexandra Sockell, Karan Vahi, Marie Verbanck, Abhishek Vishnu, Ryan W Walker, Kristin L Young, Niha Zubair, Victor Acuña-Alonso, Jose Luis Ambite, Kathleen C Barnes, Eric Boerwinkle, Erwin P Bottinger, Carlos D Bustamante, Christian Caberto, Samuel Canizales-Quinteros, Matthew P Conomos, Ewa Deelman, Ron Do, Kimberly Doheny, Lindsay Fernández-Rhodes, Myriam Fornage, Benyam Hailu, Gerardo Heiss, Brenna M Henn, Lucia A Hindorff, Rebecca D Jackson, Cecelia A Laurie, Cathy C Laurie, Yuqing Li, Dan-Yu Lin, Andres Moreno-Estrada, Girish Nadkarni, Paul J Norman, Loreall C Pooler, Alexander P Reiner, Jane Romm, Chiara Sabatti, Karla Sandoval, Xin Sheng, Eli A Stahl, Daniel O Stram, Timothy A Thornton, Christina L Wassel, Lynne R Wilkens, Cheryl A Winkler, Sachi Yoneyama, Steven Buyske, Christopher A Haiman, Charles Kooperberg, Loic Le Marchand, Ruth JF Loos, Tara C Matise, Kari E North, Ulrike Peters, Eimear E Kenny, Christopher S Carlson

Journal

Nature

Open Publication